Gene information
Official symbol IL7
Official full name interleukin 7
Gene type protein-coding gene
Chromosome8q21.13
Alias symbolIL-7
Gene familyInterleukins
Resources
Entrez Gene 3574
HGNC HGNC:6023
Ensembl ENSG00000104432
Vega OTTHUMG00000164620
UCSC uc022awh.2
GO terms: 89 records
GO Description Category LogP Number of genes Detail
GO:0001775 cell activation GO Biological Processes -43.3738118 71 More
GO:0001819 positive regulation of cytokine production GO Biological Processes -44.1872667 64 More
GO:0001894 tissue homeostasis GO Biological Processes -10.3152206 20 More
GO:0001959 regulation of cytokine-mediated signaling pathway GO Biological Processes -13.0991884 33 More
GO:0001961 positive regulation of cytokine-mediated signaling pathway GO Biological Processes -3.95887136 6 More
GO:0002360 T cell lineage commitment GO Biological Processes -3.67847337 4 More
GO:0002520 immune system development GO Biological Processes -15.2957169 80 More
GO:0002521 leukocyte differentiation GO Biological Processes -12.4650129 27 More
GO:0002694 regulation of leukocyte activation GO Biological Processes -32.0887020 60 More
GO:0002696 positive regulation of leukocyte activation GO Biological Processes -27.9249645 47 More
GO:0005125 cytokine activity GO Molecular Functions -54.7097150 57 More
GO:0005126 cytokine receptor binding GO Molecular Functions -41.4908940 50 More
GO:0006959 humoral immune response GO Biological Processes -20.5068158 33 More
GO:0008083 growth factor activity GO Molecular Functions -26.3260872 31 More
GO:0019221 cytokine-mediated signaling pathway GO Biological Processes -27.5840932 43 More
GO:0022407 regulation of cell-cell adhesion GO Biological Processes -32.4337382 53 More
GO:0022409 positive regulation of cell-cell adhesion GO Biological Processes -25.7751074 39 More
GO:0030097 hemopoiesis GO Biological Processes -14.1443585 71 More
GO:0030098 lymphocyte differentiation GO Biological Processes -7.22308617 17 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0030217 T cell differentiation GO Biological Processes -5.22709721 11 More
GO:0030312 external encapsulating structure GO Cellular Components -73.3689453 93 More
GO:0030545 signaling receptor regulator activity GO Molecular Functions -87.4728446 102 More
GO:0030546 signaling receptor activator activity GO Molecular Functions -90.4065983 101 More
GO:0030888 regulation of B cell proliferation GO Biological Processes -7.97568198 10 More
GO:0030890 positive regulation of B cell proliferation GO Biological Processes -8.50618951 9 More
GO:0031012 extracellular matrix GO Cellular Components -73.4416071 93 More
GO:0032642 regulation of chemokine production GO Biological Processes -25.2850711 37 More
GO:0032722 positive regulation of chemokine production GO Biological Processes -22.4503100 21 More
GO:0032944 regulation of mononuclear cell proliferation GO Biological Processes -24.6915018 34 More
GO:0032946 positive regulation of mononuclear cell proliferation GO Biological Processes -20.2231223 25 More
GO:0040008 regulation of growth GO Biological Processes -30.7609323 104 More
GO:0042110 T cell activation GO Biological Processes -7.78997285 18 More
GO:0043086 negative regulation of catalytic activity GO Biological Processes -41.1437610 130 More
GO:0045165 cell fate commitment GO Biological Processes -15.5778047 44 More
GO:0045321 leukocyte activation GO Biological Processes -25.4958219 48 More
GO:0045453 bone resorption GO Biological Processes -4.37707433 7 More
GO:0045577 regulation of B cell differentiation GO Biological Processes -3.16367145 4 More
GO:0045579 positive regulation of B cell differentiation GO Biological Processes -3.13889786 3 More
GO:0045580 regulation of T cell differentiation GO Biological Processes -7.18541630 25 More
GO:0045619 regulation of lymphocyte differentiation GO Biological Processes -8.78322888 17 More
GO:0045621 positive regulation of lymphocyte differentiation GO Biological Processes -6.96534841 12 More
GO:0045785 positive regulation of cell adhesion GO Biological Processes -29.6368249 50 More
GO:0045927 positive regulation of growth GO Biological Processes -20.3035639 52 More
GO:0046620 regulation of organ growth GO Biological Processes -13.2396968 26 More
GO:0046622 positive regulation of organ growth GO Biological Processes -9.67012229 16 More
GO:0046649 lymphocyte activation GO Biological Processes -10.1732143 26 More
GO:0046849 bone remodeling GO Biological Processes -4.21089449 9 More
GO:0048018 receptor ligand activity GO Molecular Functions -91.0736151 101 More
GO:0048534 hematopoietic or lymphoid organ development GO Biological Processes -16.4041704 79 More
GO:0048638 regulation of developmental growth GO Biological Processes -23.5012496 63 More
GO:0048639 positive regulation of developmental growth GO Biological Processes -14.4198804 35 More
GO:0048771 tissue remodeling GO Biological Processes -15.8777137 28 More
GO:0048871 multicellular organismal homeostasis GO Biological Processes -14.5562171 53 More
GO:0048872 homeostasis of number of cells GO Biological Processes -12.0072872 22 More
GO:0048873 homeostasis of number of cells within a tissue GO Biological Processes -5.73116566 9 More
GO:0050670 regulation of lymphocyte proliferation GO Biological Processes -22.6006415 32 More
GO:0050671 positive regulation of lymphocyte proliferation GO Biological Processes -19.1485102 24 More
GO:0050730 regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.1120967 60 More
GO:0050863 regulation of T cell activation GO Biological Processes -20.3209154 36 More
GO:0050864 regulation of B cell activation GO Biological Processes -7.98662389 16 More
GO:0050865 regulation of cell activation GO Biological Processes -40.6877761 71 More
GO:0050867 positive regulation of cell activation GO Biological Processes -31.2431659 51 More
GO:0050870 positive regulation of T cell activation GO Biological Processes -17.6497748 28 More
GO:0050871 positive regulation of B cell activation GO Biological Processes -8.77049404 15 More
GO:0051249 regulation of lymphocyte activation GO Biological Processes -22.6120519 46 More
GO:0051251 positive regulation of lymphocyte activation GO Biological Processes -20.2181987 37 More
GO:0060249 anatomical structure homeostasis GO Biological Processes -12.3640817 24 More
GO:0060759 regulation of response to cytokine stimulus GO Biological Processes -13.7003447 35 More
GO:0060760 positive regulation of response to cytokine stimulus GO Biological Processes -4.64741860 7 More
GO:0062023 collagen-containing extracellular matrix GO Cellular Components -67.6170082 80 More
GO:0070663 regulation of leukocyte proliferation GO Biological Processes -26.8242532 37 More
GO:0070665 positive regulation of leukocyte proliferation GO Biological Processes -21.5362473 27 More
GO:0070851 growth factor receptor binding GO Molecular Functions -16.9609899 22 More
GO:0071345 cellular response to cytokine stimulus GO Biological Processes -39.647808 70 More
GO:1901099 negative regulation of signal transduction in absence of ligand GO Biological Processes -4.18352224 5 More
GO:1902105 regulation of leukocyte differentiation GO Biological Processes -18.8286876 32 More
GO:1902107 positive regulation of leukocyte differentiation GO Biological Processes -14.6775052 22 More
GO:1903037 regulation of leukocyte cell-cell adhesion GO Biological Processes -23.2079690 66 More
GO:1903039 positive regulation of leukocyte cell-cell adhesion GO Biological Processes -20.7355312 32 More
GO:1903131 mononuclear cell differentiation GO Biological Processes -9.35861236 21 More
GO:1903706 regulation of hemopoiesis GO Biological Processes -16.2759166 33 More
GO:1903708 positive regulation of hemopoiesis GO Biological Processes -14.6775052 22 More
GO:2001233 regulation of apoptotic signaling pathway GO Biological Processes -35.8481080 51 More
GO:2001234 negative regulation of apoptotic signaling pathway GO Biological Processes -32.1748782 40 More
GO:2001236 regulation of extrinsic apoptotic signaling pathway GO Biological Processes -20.7647111 26 More
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway GO Biological Processes -19.1764933 21 More
GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand GO Biological Processes -4.65044629 6 More
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO Biological Processes -4.18352224 5 More
KEGG pathways: 5 records
KEGG Description Category LogP Number of genes Detail
hsa04060 Cytokine-cytokine receptor interaction KEGG Pathway -61.0014447 66 More
hsa04151 PI3K-Akt signaling pathway KEGG Pathway -29.3006421 73 More
hsa04630 JAK-STAT signaling pathway KEGG Pathway -14.4088859 21 More
hsa04640 Hematopoietic cell lineage KEGG Pathway -11.4657972 15 More
hsa05200 Pathways in cancer KEGG Pathway -30.6393212 92 More
Drug-Gene interaction
view
Related drugs: 1 record
Drug name Interaction type Source PMID View
sirolimus NCI 14657335 view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
interleukin-7 proteomics poor predictor death[prognosis (bad)] acute myocardial infarction Prondzinsky R et al. Clin Res Cardiol. 2012
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